Arizona Cardinals at Los Angeles Chargers -- NFL Week 1, September 13, 2026.
Model prediction: Los Angeles Chargers favored by 9.5, projected total 40.2 points, 73.7% win probability for Los Angeles Chargers.
Prediction last recalculated August 30, 2026 at 6:00 AM UTC.
Market spread: Los Angeles Chargers -10.5.
Simulated range of outcomes (10,000 simulations) -- home margin 10th percentile: -7.5, 25th percentile: +0.6, 50th percentile: +9.7, 75th percentile: +18.7, 90th percentile: +27.0. Total points 10th percentile: 22.6, 25th percentile: 30.7, 50th percentile: 40.1, 75th percentile: 49.4, 90th percentile: 57.7.
LAC predicted starting offense vs ARI's Base 4-3 D: WR Ladd McConkey, WR Quentin Johnston, LT Rashawn Slater, LG Kayode Awosika, C Jake Slaughter, RG Cole Strange, RT Joe Alt, WR Tre Harris, QB Justin Herbert, TE Charlie Kolar, TE David Njoku, RB Omarion Hampton, FB Alec Ingold.
ARI predicted starting offense vs LAC's Base 3-4 D: WR Marvin Harrison, WR Michael Wilson, LT Paris Johnson, LG Isaac Seumalo, C Hjalte Froholdt, RG Isaiah Adams, RT Elijah Wilkinson, WR Kendrick Bourne, QB Jacoby Brissett, TE Trey McBride, TE Tip Reiman, RB Jeremiyah Love.
ARI's offensive depth chart isn't fully set yet (12/13 slots known). LAC leans pass-heavy (75% of recent snaps) against ARI's Base 4-3 D. ARI leans pass-heavy (75% of recent snaps) against LAC's Base 3-4 D.
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